Pulmonary Aspergillus and Mucor Co-Infection

Co-infections or consecutive infections of mucormycosis and aspergillosis are very rare. Additionally, distinguishing between these two is also difficult as both conditions have similar clinical features. We report cases from Tamilnadu, who presented to a tertiary care centre in Puducherry, India 2017 (first case) 2019 (second case).The first case was 70-year-old, non-diabetic male patient with haemoptysis prior history pulmonary tuberculosis. Computed tomography bronchial angiography revealed an air-crescent sign the histopathological examination showed fungal ball (aspergillus mucor) upper lobe foci infection middle lobe. The second 65-year-old diabetic blackish expectoration haemoptysis. A high-resolution computed scan reverse-halo right results bronchoscopy-guided biopsy were consistent diagnosis mixed angioinvasion. Both patients responded amphotericin B surgical excision affected case.A high degree suspicion, early intervention antifungal therapy essential treatment this rare co-infection.
 Keywords:Aspergillosis; Mucormycosis; Bronchoscopy; Coinfection; Amphotericin B; Case Report; India.